(3s,4r)-tert-butyl 3-amino-4-phenylpyrrolidine-1-carboxylate - Names and Identifiers
(3s,4r)-tert-butyl 3-amino-4-phenylpyrrolidine-1-carboxylate - Physico-chemical Properties
Molecular Formula | C15H22N2O2
|
Molar Mass | 262.35 |
Density | 1.09±0.1 g/cm3(Predicted) |
Boling Point | 401.1±45.0 °C(Predicted) |
pKa | 12.10±0.40(Predicted) |
Storage Condition | Room Temprature |
(3s,4r)-tert-butyl 3-amino-4-phenylpyrrolidine-1-carboxylate - Introduction
N-Boc-3-amino-4-phenylpyrrolidine(N-Boc-3-amino-4-phenylpyrrolidine) is an organic compound. Its properties are as follows:
1. Appearance: white or almost white crystalline powder.
2. molecular formula: C15H22N2O2.
3. Molecular weight: 262.35g/mol.
4. melting point: about 85-87 ℃.
5. solubility: soluble in ester, ether, methylene chloride and acetonitrile, insoluble in water.
N-Boc-3-amino-4-phenylpyrrolidine can be used as chemical intermediates in organic synthesis reactions. It is often used in the preparation of biologically active compounds, such as drugs, natural products and heterocyclic compounds. It can also be used as a starting compound for organic synthesis, prepared by amination of tert-butyl carbamate.
The method of preparing N-Boc-3-amino-4-phenylpyrrolidine is relatively simple. A commonly used method is to react 3-amino-4-phenyl pyrrolidine with tert-butoxycarbonyl ammonium chloride to generate N-Boc-3-amino-4-phenylpyrrolidine. In this process, attention should be paid to the operating conditions and efficient stirring to improve the reaction efficiency.
As for safety information, N-Boc-3-amino-4-phenylpyrrolidine may irritate the eyes, skin and respiratory tract. In case of contact, take appropriate protective measures, such as wearing protective glasses and gloves, and ensure that the operation is carried out in a well-ventilated place. In addition, it is also a flammable compound and should be kept away from fire sources, electric sparks and high temperatures. During use, please follow the relevant safety guidelines and pay attention to personal protection.
Last Update:2024-04-09 22:09:11